This book presents the outcomes of the 5th ACIS International Conference on Computational Science/Intelligence & Applied Informatics (CSII 2018), which was held on July 10-12, 2018 in Yonago, Japan. The aim of the conference was to bring together researchers and scientists, businesspeople and entrepreneurs, teachers, engineers, computer users, and students to discuss the various fields of computer science, to share their experiences, and to exchange new ideas and information in a meaningful way.